SLC35E3

Across TCGA cell cohorts, SLC35E3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,015 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC35E3-associated genes across cancer lineages are SNX3, ELK3, and PACS2. Each is linked with SLC35E3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35E3-to-partner and partner-to-SLC35E3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC35E3 versus SNX3 in LARGE_INTESTINE, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E3→partner) and Y-score (partner→SLC35E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNX3 →	-1.118	-1.460	.003	.001	3	3
BLOOD_Lymphoma	ELK3 →	+2.301	+2.022	<.001	.002	3	3
BLOOD_Lymphoma	PACS2 →	+1.404	+2.021	.002	.002	3	3
BREAST	MAGIX →	+1.254	+1.126	.001	.008	3	3
LARGE_INTESTINE	FBXO7 →	-0.681	-1.300	.004	.006	3	2
LARGE_INTESTINE	C1QBP →	-1.144	-1.460	<.001	.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,015 associations by consensus.

SLC35E3 vs SNX3 — LARGE_INTESTINE

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