Across TCGA pan-cancer cohorts, SLC35E2B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35E2B data layer compared with 23 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher SLC35E2B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC35E2B expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.
OV, UCEC, and LUAD are the cancer types where SLC35E2B mass-spec protein most reproducibly stratifies survival.