Across TCGA patient cohorts, SLC35E2B mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35E2B-associated genes across cancer lineages are ERK2, GATA3, and GATA6. Each is linked with SLC35E2B in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35E2B-to-partner and partner-to-SLC35E2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E2B→partner) and Y-score (partner→SLC35E2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.253	+2.415	.001	.003	3	1
UCEC	GATA3 →	+0.160	+1.498	.035	.036	3	1
UCEC	GATA6 →	-0.139	-2.985	.034	.034	3	1
UCEC	mTOR_pS2448 →	-0.143	-2.302	.017	.034	3	1
UCEC	NF-kB-p65_pS536 →	-0.366	-1.990	.045	.030	3	1
UCEC	PDCD4 →	-0.554	-1.874	.003	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

SLC35E2B survival (RNA) · tumor vs normal (RNA) · all SLC35E2B data types