Across TCGA patient cohorts, SLC35E2A mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35E2A-associated genes across cancer lineages are RNU6-492P, RNA5SP436, and RN7SKP118. Each is linked with SLC35E2A in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35E2A-to-partner and partner-to-SLC35E2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35E2A→partner) and Y-score (partner→SLC35E2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	3
UCEC	RNA5SP436 →	+1.269	+5.522	<.001	<.001	3	2
CESC	RN7SKP118 →	+0.158	+5.103	<.001	.008	3	1
CESC	H3P29 →	+0.141	+5.201	<.001	.007	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
CESC	FAM224A →	+0.028	+5.812	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

SLC35E2A survival (RNA) · tumor vs normal (RNA) · all SLC35E2A data types