SLC35E1

Across TCGA pan-cancer cohorts, SLC35E1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35E1 data layer compared with 31 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SLC35E1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35E1 expression acts as an unfavorable survival marker.

LUSC, LIHC, and LUAD are the cancer types where SLC35E1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.231	0.758	.017	18	view →
LIHC	DFS	Median	All	0.099	0.557	<.001	18	view →
LUAD	OS	Median	All	0.238	0.697	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC35E1–LUSC (DFS)

Open the LUSC breakdown →