SLC35E1

Across TCGA pan-cancer cohorts, SLC35E1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC35E1 data layer compared with 31 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC35E1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC35E1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where SLC35E1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.849	0.247	.002	35	view →
CCRCC	OS	Median	All	0.637	1.000	.003	21	view →
PDAC	DFS	Tertile	II,III,IV	0.260	0.512	.006	20	view →
UCEC	DFS	Median	All	0.789	0.930	.030	4	view →
HNSC	DFS	Median	All	0.978	0.925	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC35E1–LUAD (OS)

Open the LUAD breakdown →