SLC35D3

Across TCGA patient cohorts, SLC35D3 mutation is significantly associated with the RNA expression of many other genes, with 754 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35D3-associated genes across cancer lineages are LINC01596, GAGE2E, and SMCO4. Each is linked with SLC35D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D3-to-partner and partner-to-SLC35D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01596 grouped by SLC35D3-low versus SLC35D3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D3→partner) and Y-score (partner→SLC35D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01596 →	+0.183	+3.061	.001	.005	3	2
COAD	GAGE2E →	+0.052	+5.568	<.001	<.001	3	2
UCEC	SMCO4 →	+0.584	+3.502	.004	.002	3	2
UCEC	CHAF1A →	+0.530	+2.743	.001	.002	3	2
UCEC	EIF1 →	+0.299	+2.988	.007	<.001	3	2
UCEC	FAS →	+0.799	+3.870	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 754 associations by consensus.

LINC01596 by SLC35D3 expression — COAD

Explore this box plot interactively →