SLC35D3

Across TCGA patient cohorts, SLC35D3 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35D3-associated genes across cancer lineages are ATM, Annexin-1, and JNK2. Each is linked with SLC35D3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35D3-to-partner and partner-to-SLC35D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC35D3-low versus SLC35D3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D3→partner) and Y-score (partner→SLC35D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.567	-2.446	.001	.018	3	3
UCEC	Annexin-1 →	+0.527	+3.720	.009	<.001	3	2
UCEC	JNK2 →	+0.215	+2.469	.004	.010	3	1
UCEC	PDCD4 →	-0.393	-2.459	.029	.018	3	1
UCEC	Rad50 →	-0.213	-2.584	.022	.001	3	1
UCEC	c-Myc →	-0.198	-2.074	.035	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ATM by SLC35D3 expression — UCEC

Explore this box plot interactively →