SLC35D3

Across TCGA cell cohorts, SLC35D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,640 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC35D3-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of syncytium formation by plasma membrane fusion, and Detoxification of inorganic compound. Each is linked with SLC35D3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC35D3-to-partner and partner-to-SLC35D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by SLC35D3-low versus SLC35D3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D3→partner) and Y-score (partner→SLC35D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.080	+0.073	<.001	.005	3	6
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.095	+2.116	.002	.004	3	6
LARGE_INTESTINE	Detoxification of inorganic compound →	-0.176	-1.147	<.001	.009	3	6
BLOOD_Lymphoma	Microtubule-based transport →	+0.028	+0.023	<.001	.003	3	5
SOFT_TISSUE	Optic nerve development →	-0.224	-0.271	.001	.005	2	6
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.086	+0.079	.006	.003	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,640 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by SLC35D3 expression — CNS

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