SLC35D3

Across TCGA cell cohorts, SLC35D3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC35D3-associated genes across cancer lineages are ASB17, OR10J5, and TINAG. Each is linked with SLC35D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D3-to-partner and partner-to-SLC35D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by SLC35D3-low versus SLC35D3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D3→partner) and Y-score (partner→SLC35D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ASB17 →	+0.035	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR10J5 →	+0.019	+5.228	<.001	.005	3	1
SKIN	TINAG →	+0.308	+3.678	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ASB17 by SLC35D3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →