SLC35D2

Across TCGA patient cohorts, SLC35D2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,209 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC35D2-associated genes across cancer lineages are PIEZO1, PLEKHG1, and RDH10. Each is linked with SLC35D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D2-to-partner and partner-to-SLC35D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC35D2 versus PIEZO1 in UCEC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D2→partner) and Y-score (partner→SLC35D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIEZO1 →	+1.359	+0.500	<.001	.006	3	1
UCEC	PLEKHG1 →	+1.300	+0.639	.003	.002	3	1
UCEC	RDH10 →	+1.753	+0.503	.002	.007	3	1
UCEC	WFIKKN1 →	-1.068	-0.460	.007	.001	3	1
UCEC	FOXA1 →	+3.721	+0.490	<.001	.002	3	1
UCEC	ADAMDEC1 →	+1.664	+0.466	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,209 associations by consensus.

SLC35D2 vs PIEZO1 — UCEC

Explore this scatter interactively →