SLC35D2

Across TCGA patient cohorts, SLC35D2 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35D2-associated genes across cancer lineages are 14-3-3_beta, eEF2, and eIF4G. Each is linked with SLC35D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D2-to-partner and partner-to-SLC35D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by SLC35D2-low versus SLC35D2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D2→partner) and Y-score (partner→SLC35D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.103	-2.432	.007	.018	3	1
UCEC	eEF2 →	+0.331	+3.321	.015	.009	3	1
UCEC	eIF4G →	+0.298	+3.321	.012	.009	3	1
UCEC	A-Raf_pS299 →	-0.162	-2.807	<.001	.003	3	1
UCEC	FOXO3a_pS318_S321 →	-0.113	-2.105	.017	.017	3	1
UCEC	GATA6 →	-0.124	-1.577	.041	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

14-3-3_beta by SLC35D2 expression — UCEC

Explore this box plot interactively →