SLC35D2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35D2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35D2-associated genes across cancer lineages are TNP1 and MAGEB4. Each is linked with SLC35D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D2-to-partner and partner-to-SLC35D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by SLC35D2-low versus SLC35D2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D2→partner) and Y-score (partner→SLC35D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETNP1 →+0.172+5.415<.001.00431
LARGE_INTESTINEMAGEB4 →+0.012+5.415.009.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TNP1 by SLC35D2 expression — LARGE_INTESTINE

Box plot of TNP1 in SLC35D2-low vs SLC35D2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration