SLC35D1

Across TCGA pan-cancer cohorts, SLC35D1 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SLC35D1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC35D1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SLC35D1 is over-expressed in tumor.

HNSC, OV, and CCRCC are the cancer types where SLC35D1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC35D1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.414	.010	4	view →
OV	All	All	+0.987	.008	2	view →
CCRCC	Male	IV	+0.930	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SLC35D1–HNSC

Open the HNSC breakdown →