SLC35D1

Across TCGA patient cohorts, SLC35D1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35D1-associated genes across cancer lineages are DC, Th2 cells, and CD8+ naive T-cells. Each is linked with SLC35D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D1-to-partner and partner-to-SLC35D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DC grouped by SLC35D1-low versus SLC35D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D1→partner) and Y-score (partner→SLC35D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DC →	+0.021	+1.688	.016	.045	3	2
UCEC	Th2 cells →	+0.163	+2.818	.038	.035	3	2
UCEC	CD8+ naive T-cells →	+0.036	+3.354	.002	.005	3	1
UCEC	Memory B-cells →	+0.028	+1.730	.016	.033	3	1
UCEC	B-cells →	+0.023	+1.573	.049	.035	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

DC by SLC35D1 expression — UCEC

Explore this box plot interactively →