SLC35D1

Across TCGA cell cohorts, SLC35D1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC35D1-associated genes across cancer lineages are HYAL4, MMP20, and SERPINA12. Each is linked with SLC35D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D1-to-partner and partner-to-SLC35D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HYAL4 grouped by SLC35D1-low versus SLC35D1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D1→partner) and Y-score (partner→SLC35D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HYAL4 →	+1.438	+3.769	<.001	.008	3	1
BLOOD_Leukemia	MMP20 →	+0.063	+3.705	<.001	.007	3	1
BLOOD_Leukemia	SERPINA12 →	+0.047	+4.060	<.001	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.278	+3.874	<.001	.005	3	1
BLOOD_Leukemia	DSG4 →	+0.033	+4.269	<.001	.002	3	1
BLOOD_Leukemia	TMEM244 →	+0.277	+3.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

HYAL4 by SLC35D1 expression — BLOOD_Leukemia

Explore this box plot interactively →