SLC35D1

Across TCGA cell cohorts, SLC35D1 mutation is significantly associated with the mutation status of many other genes, with 270 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC35D1-associated genes across cancer lineages are IQCA1, GFM2, and RANBP17. Each is linked with SLC35D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35D1-to-partner and partner-to-SLC35D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCA1 grouped by SLC35D1-low versus SLC35D1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35D1→partner) and Y-score (partner→SLC35D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IQCA1 →	+3.870	+4.050	.002	.002	1	2
OVARY	GFM2 →	+4.977	+4.415	.007	.007	1	2
OVARY	RANBP17 →	+4.977	+4.415	.007	.007	1	2
OVARY	ARHGAP21 →	+4.977	+4.415	.007	.007	1	2
LARGE_INTESTINE	NIT1 →	+4.523	+5.087	.006	.006	1	2
BLOOD_Leukemia	GCAT →	+3.548	+3.845	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

IQCA1 by SLC35D1 expression — BLOOD_Leukemia

Explore this box plot interactively →