SLC35C2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC35C2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35C2 data layer compared with 24 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SLC35C2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC35C2 expression acts as an unfavorable survival marker.

BRCA, OV, and UCEC are the cancer types where SLC35C2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSMedianAll0.0640.924<.00148view →
OVDFSMedianII,III,IV0.1400.541.00118view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC35C2–BRCA (OS)

Kaplan–Meier survival curve for SLC35C2 mutant vs wild-type samples in BRCA.

Open the BRCA breakdown →

Exploration