SLC35C2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC35C2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35C2 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SLC35C2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35C2 expression acts as an unfavorable survival marker.

PDAC, LUAD, and HNSC are the cancer types where SLC35C2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSQuartileAll0.2580.877.01027view →
LUADDFSMedianIII,IV0.2510.899.01013view →
HNSCDFSMedianIII,IV0.9061.000.0273view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC35C2–PDAC (DFS)

Kaplan–Meier survival curve for SLC35C2 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration