SLC35C2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35C2 mutation is significantly associated with the RNA expression of many other genes, with 2,613 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35C2-associated genes across cancer lineages are MTND2P4, OR55B1P, and LINC02559. Each is linked with SLC35C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35C2-to-partner and partner-to-SLC35C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND2P4 grouped by SLC35C2-low versus SLC35C2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35C2→partner) and Y-score (partner→SLC35C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADMTND2P4 →+0.064+3.572<.001.00732
CESCOR55B1P →+0.061+3.376<.001.00732
CESCLINC02559 →+0.674+4.342<.001.00732
CESCPLGLA →+0.157+4.626<.001<.00132
BLCARNU6-1289P →+0.337+5.033<.001.00332
BLCAMIR760 →+0.488+4.004.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,613 associations by consensus.

MTND2P4 by SLC35C2 expression — LUAD

Box plot of MTND2P4 in SLC35C2-low vs SLC35C2-high samples in LUAD.

Explore this box plot interactively →

Exploration