SLC35C2

Across TCGA cell cohorts, SLC35C2 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35C2-associated genes across cancer lineages are OTUD6A, LYPD4, and SRSF12. Each is linked with SLC35C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35C2-to-partner and partner-to-SLC35C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OTUD6A grouped by SLC35C2-low versus SLC35C2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35C2→partner) and Y-score (partner→SLC35C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OTUD6A →	+0.113	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	LYPD4 →	+0.128	+4.867	<.001	.009	3	1
LARGE_INTESTINE	SRSF12 →	+0.398	+3.392	.001	.006	3	1
LARGE_INTESTINE	SSMEM1 →	+0.028	+3.029	<.001	.006	3	1
LARGE_INTESTINE	CPLX4 →	+0.027	+4.029	<.001	.001	3	1
LARGE_INTESTINE	PNMA3 →	+0.196	+3.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

OTUD6A by SLC35C2 expression — BLOOD_Lymphoma

Explore this box plot interactively →