SLC35C1

Across TCGA patient cohorts, SLC35C1 mutation is significantly associated with the RNA expression of many other genes, with 446 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35C1-associated genes across cancer lineages are MIR676, MIR6864, and OR10A6. Each is linked with SLC35C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35C1-to-partner and partner-to-SLC35C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR676 grouped by SLC35C1-low versus SLC35C1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35C1→partner) and Y-score (partner→SLC35C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR676 →	+0.443	+5.044	<.001	.009	3	3
UCEC	MIR6864 →	+0.648	+2.224	.001	.008	3	2
LUSC	OR10A6 →	+0.067	+5.235	<.001	.001	3	2
SKCM	PPIAL4F →	+0.072	+4.333	.002	.001	3	2
LUAD	RNA5SP162 →	+0.697	+5.888	<.001	.002	3	2
UCEC	RNA5SP417 →	+0.529	+2.866	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

MIR676 by SLC35C1 expression — LUAD

Explore this box plot interactively →