SLC35C1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35C1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35C1-associated genes across cancer lineages are Fibroblasts, Neutrophils, and Endothelial cells. Each is linked with SLC35C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35C1-to-partner and partner-to-SLC35C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by SLC35C1-low versus SLC35C1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35C1→partner) and Y-score (partner→SLC35C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADFibroblasts →+0.025+5.721.044.03631
UCECNeutrophils →+0.013+1.681.006.04931
UCECEndothelial cells →-0.041-2.279.030.03621
UCEClymphatic Endothelial cells →-0.027-2.268.024.03611
UCECmv Endothelial cells →-0.029-3.448.015.00511
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Fibroblasts by SLC35C1 expression — COAD

Box plot of Fibroblasts in SLC35C1-low vs SLC35C1-high samples in COAD.

Explore this box plot interactively →

Exploration