SLC35C1

Across TCGA cell cohorts, SLC35C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,390 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC35C1-associated GO terms across cancer lineages are 'de novo' GDP-L-fucose biosynthetic process, Nucleotide-sugar transmembrane transport, and GDP-mannose metabolic process. Each is linked with SLC35C1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC35C1-to-partner and partner-to-SLC35C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' GDP-L-fucose biosynthetic process grouped by SLC35C1-low versus SLC35C1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35C1→partner) and Y-score (partner→SLC35C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	'de novo' GDP-L-fucose biosynthetic process →	+0.244	+1.651	.001	.002	3	18
BLOOD_Myeloma	Nucleotide-sugar transmembrane transport →	+0.135	+1.102	<.001	<.001	3	16
PANCREAS	GDP-mannose metabolic process →	+0.139	+1.169	<.001	<.001	3	15
BLOOD_Myeloma	Cytosol to Golgi apparatus transport →	+0.121	+0.865	.005	.003	2	15
UPPER_AERODIGESTIVE_TRACT	Viral gene expression →	+0.112	+1.013	<.001	.001	3	12
OESOPHAGUS	Carbohydrate homeostasis →	+0.058	+1.630	.007	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,390 associations by consensus.

'de novo' GDP-L-fucose biosynthetic process by SLC35C1 expression — LIVER

Explore this box plot interactively →