Across TCGA pan-cancer cohorts, SLC35B4 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35B4 data layer compared with 29 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher SLC35B4 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35B4 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KICH, HNSC, and UCEC are the cancer types where SLC35B4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.025	0.904	<.001	36	view →
HNSC	DFS	Median	All	0.180	0.710	.009	12	view →
UCEC	DFS	Median	II,III,IV	1.000	0.446	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SLC35B4 tumor-vs-normal RNA expression · all SLC35B4 data types