Across TCGA patient cohorts, SLC35B4 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35B4-associated genes across cancer lineages are PKC-a_pS657, PKC-a, and Rab11. Each is linked with SLC35B4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B4-to-partner and partner-to-SLC35B4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B4→partner) and Y-score (partner→SLC35B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-a_pS657 →	+0.572	+3.335	.004	.005	3	1
UCEC	PKC-a →	+0.679	+3.183	.001	.009	3	1
UCEC	Rab11 →	-0.188	-3.321	.013	.010	3	1
UCEC	VHL →	-0.919	-3.000	.009	.036	3	1
UCEC	Caspase-8 →	-0.297	-3.143	.024	.018	3	1
UCEC	p62 Lck ligand →	+0.682	+3.321	<.001	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

SLC35B4 survival (RNA) · tumor vs normal (RNA) · all SLC35B4 data types