Across TCGA cell cohorts, SLC35B4 mutation is significantly associated with the drug of many other genes, with 61 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35B4-associated genes across cancer lineages are Docetaxel, Methotrexate, and Lenalidomide. Each is linked with SLC35B4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B4-to-partner and partner-to-SLC35B4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B4→partner) and Y-score (partner→SLC35B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Docetaxel →	+0.648	+2.807	.018	.046	3	1
LARGE_INTESTINE	Methotrexate →	+1.149	+2.807	.002	.035	3	1
LARGE_INTESTINE	Lenalidomide →	+0.348	+2.807	.010	.046	3	1
LARGE_INTESTINE	Mirin →	+0.382	+2.868	.033	.022	3	1
LARGE_INTESTINE	MK-1775 →	+0.342	+2.868	.026	.022	3	1
LARGE_INTESTINE	Epirubicin →	+0.731	+2.871	.004	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

SLC35B4 survival (RNA) · tumor vs normal (RNA) · all SLC35B4 data types