SLC35B3

Across TCGA pan-cancer cohorts, SLC35B3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC35B3 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC35B3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC35B3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

HNSC, CCRCC, and GBM are the cancer types where SLC35B3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.499	0.973	.031	24	view →
CCRCC	DFS	Quartile	II,III,IV	0.907	0.393	.019	11	view →
GBM	OS	Quartile	All	0.158	0.488	.030	6	view →
PDAC	DFS	Median	IV	0.199	0.621	.010	6	view →
LSCC	DFS	Median	III,IV	0.582	0.941	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC35B3–HNSC (OS)

Open the HNSC breakdown →