SLC35B2

Across TCGA pan-cancer cohorts, SLC35B2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC35B2 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC35B2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35B2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

LUAD, HNSC, and CCRCC are the cancer types where SLC35B2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.773	1.000	.005	13	view →
HNSC	OS	Median	All	0.449	1.000	.023	12	view →
CCRCC	OS	Median	All	1.000	0.911	.023	7	view →
UCEC	OS	Quartile	All	1.000	0.894	.035	2	view →
PDAC	OS	Tertile	III,IV	1.000	0.506	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC35B2–LUAD (DFS)

Open the LUAD breakdown →