SLC35B2

Across TCGA patient cohorts, SLC35B2 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35B2-associated genes across cancer lineages are Annexin-1, Caspase-7-cleavedD198, and 14-3-3_beta. Each is linked with SLC35B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B2-to-partner and partner-to-SLC35B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by SLC35B2-low versus SLC35B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B2→partner) and Y-score (partner→SLC35B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.736	+2.827	.010	.035	3	1
UCEC	Caspase-7-cleavedD198 →	+1.049	+2.827	.001	.035	3	1
UCEC	14-3-3_beta →	-0.151	-3.156	.006	.020	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Annexin-1 by SLC35B2 expression — UCEC

Explore this box plot interactively →