SLC35B1

Across TCGA pan-cancer cohorts, SLC35B1 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SLC35B1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SLC35B1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types SLC35B1 is over-expressed in tumor, although a few such as LUAD and PDAC show the opposite, repressed pattern.

LUAD, CCRCC, and PDAC are the cancer types where SLC35B1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC35B1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.505	<.001	6	view →
CCRCC	All	II,III,IV	+0.800	.008	1	view →
PDAC	All	All	−0.318	.038	1	view →
LSCC	Male	All	−0.250	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SLC35B1–LUAD

Open the LUAD breakdown →