SLC35B1

Across TCGA patient cohorts, SLC35B1 mutation is significantly associated with the RNA expression of many other genes, with 825 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35B1-associated genes across cancer lineages are MIR325, ANP32BP2, and MIR3691. Each is linked with SLC35B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B1-to-partner and partner-to-SLC35B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR325 grouped by SLC35B1-low versus SLC35B1-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B1→partner) and Y-score (partner→SLC35B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	MIR325 →	+0.258	+7.962	<.001	.007	3	2
UCEC	ANP32BP2 →	+0.189	+2.051	<.001	.006	3	2
CESC	MIR3691 →	+0.601	+5.669	<.001	.003	3	2
BRCA	RNU6-543P →	+0.283	+8.055	<.001	.007	3	2
SKCM	PSMB7P1 →	+0.055	+4.469	<.001	.006	3	2
COAD	MTND4LP2 →	+0.206	+4.721	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 825 associations by consensus.

MIR325 by SLC35B1 expression — THCA

Explore this box plot interactively →