SLC35B1

Across TCGA patient cohorts, SLC35B1 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35B1-associated genes across cancer lineages are IGFBP2, JNK2, and p27_pT157. Each is linked with SLC35B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B1-to-partner and partner-to-SLC35B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by SLC35B1-low versus SLC35B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B1→partner) and Y-score (partner→SLC35B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.924	-2.000	.001	.032	3	1
UCEC	JNK2 →	+0.183	+2.000	.041	.032	3	1
UCEC	p27_pT157 →	-0.057	-2.000	.029	.032	3	1
UCEC	P-Cadherin →	-0.152	-2.999	.019	.035	3	1
UCEC	PCNA →	+0.213	+2.700	.028	.006	3	1
UCEC	PKC-delta_pS664 →	-0.131	-3.169	.015	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

IGFBP2 by SLC35B1 expression — UCEC

Explore this box plot interactively →