SLC35B1

Across TCGA cell cohorts, SLC35B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,052 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SLC35B1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11), and Regulation of centrosome cycle. Each is linked with SLC35B1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC35B1-to-partner and partner-to-SLC35B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by SLC35B1-low versus SLC35B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B1→partner) and Y-score (partner→SLC35B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.092	+0.455	.002	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.114	+0.831	.004	.001	3	10
PANCREAS	Regulation of centrosome cycle →	+0.048	+0.583	.001	<.001	3	10
BLOOD_Lymphoma	Multi-pass transmembrane protein insertion into ER membrane →	+0.151	+0.921	<.001	<.001	3	10
SKIN	Lysosome organization →	+0.065	+0.641	<.001	<.001	3	10
SKIN	Lytic vacuole organization →	+0.065	+0.641	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,052 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by SLC35B1 expression — BONE

Explore this box plot interactively →