Across TCGA pan-cancer cohorts, SLC35A5 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC35A5 data layer compared with 20 for mass-spec protein and 3 for mass-spec protein.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher SLC35A5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC35A5 expression acts as an unfavorable survival marker.
LIHC and UCEC are the cancer types where SLC35A5 Mutation most reproducibly stratifies survival.