SLC35A5

Across TCGA pan-cancer cohorts, SLC35A5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC35A5 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC35A5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC35A5 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where SLC35A5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.367	0.800	<.001	43	view →
PDAC	DFS	Median	All	0.192	0.419	.031	9	view →
LSCC	OS	Quartile	II,III,IV	0.853	0.550	.042	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC35A5–LUAD (DFS)

Open the LUAD breakdown →