SLC35A5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35A5 mutation is significantly associated with the RNA expression of many other genes, with 449 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A5-associated genes across cancer lineages are LINC00440, RNU4-63P, and DOLPP1. Each is linked with SLC35A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A5-to-partner and partner-to-SLC35A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00440 grouped by SLC35A5-low versus SLC35A5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A5→partner) and Y-score (partner→SLC35A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC00440 →+0.121+5.579<.001.00132
SKCMRNU4-63P →+0.150+4.212<.001.00732
UCECDOLPP1 →+0.620+3.595.002.00132
UCECRNU6-32P →+0.746+3.081<.001<.00132
UCECRNU6-1242P →+0.311+2.589.004.00832
UCECFDX1P2 →+0.133+3.123.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 449 associations by consensus.

LINC00440 by SLC35A5 expression — CESC

Box plot of LINC00440 in SLC35A5-low vs SLC35A5-high samples in CESC.

Explore this box plot interactively →

Exploration