SLC35A5

Across TCGA patient cohorts, SLC35A5 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A5-associated genes across cancer lineages are GAPDH, JNK_pT183_Y185, and Notch1. Each is linked with SLC35A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A5-to-partner and partner-to-SLC35A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by SLC35A5-low versus SLC35A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A5→partner) and Y-score (partner→SLC35A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.776	+3.000	.012	.037	3	1
UCEC	JNK_pT183_Y185 →	-0.240	-2.986	.013	.037	3	1
UCEC	Notch1 →	+0.266	+2.820	.001	.035	3	1
UCEC	STAT3_pY705 →	-0.629	-2.990	<.001	.036	3	1
UCEC	Tuberin →	+0.527	+2.817	<.001	.036	3	1
UCEC	Cyclin-E2 →	+0.290	+2.817	.002	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

GAPDH by SLC35A5 expression — UCEC

Explore this box plot interactively →