SLC35A5

Across TCGA cell cohorts, SLC35A5 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC35A5-associated genes across cancer lineages are PRAMEF26, REG3G, and MAGEB18. Each is linked with SLC35A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A5-to-partner and partner-to-SLC35A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF26 grouped by SLC35A5-low versus SLC35A5-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A5→partner) and Y-score (partner→SLC35A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PRAMEF26 →	+0.270	+5.754	.005	.002	3	1
BLOOD_Leukemia	REG3G →	+0.093	+4.874	<.001	.002	3	1
BLOOD_Leukemia	MAGEB18 →	+0.124	+4.152	<.001	.009	3	1
BLOOD_Leukemia	VSTM2B →	+0.107	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR8D1 →	+0.121	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR8D2 →	+0.111	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

PRAMEF26 by SLC35A5 expression — CNS

Explore this box plot interactively →