SLC35A3

Across TCGA patient cohorts, SLC35A3 mutation is significantly associated with the RNA expression of many other genes, with 1,880 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A3-associated genes across cancer lineages are RNU7-105P, RNU2-47P, and OR2W5. Each is linked with SLC35A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A3-to-partner and partner-to-SLC35A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-105P grouped by SLC35A3-low versus SLC35A3-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A3→partner) and Y-score (partner→SLC35A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU7-105P →	+0.448	+4.529	<.001	.009	3	2
UCEC	RNU2-47P →	+0.077	+3.973	<.001	.006	3	2
SKCM	OR2W5 →	+0.032	+5.080	<.001	.004	3	1
SKCM	RNU1-136P →	+0.334	+4.324	<.001	.007	3	1
SKCM	SLC25A51P1 →	+0.063	+4.680	<.001	.007	3	1
SKCM	CIBAR1P2 →	+0.037	+4.352	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,880 associations by consensus.

RNU7-105P by SLC35A3 expression — LGG

Explore this box plot interactively →