SLC35A2

Across TCGA patient cohorts, SLC35A2 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A2-associated genes across cancer lineages are JNK2, 14-3-3_beta, and EGFR_pY1068. Each is linked with SLC35A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A2-to-partner and partner-to-SLC35A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by SLC35A2-low versus SLC35A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A2→partner) and Y-score (partner→SLC35A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.196	+2.273	.001	<.001	3	2
UCEC	14-3-3_beta →	-0.088	-3.780	.003	<.001	3	1
UCEC	EGFR_pY1068 →	-0.235	-1.440	.001	.022	3	1
UCEC	eIF4E →	+0.176	+2.392	.005	<.001	3	1
UCEC	A-Raf_pS299 →	-0.086	-1.321	.017	.012	3	1
UCEC	ERK2 →	+0.153	+2.807	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

JNK2 by SLC35A2 expression — UCEC

Explore this box plot interactively →