SLC35A1

Across TCGA patient cohorts, SLC35A1 mutation is significantly associated with the RNA expression of many other genes, with 1,028 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35A1-associated genes across cancer lineages are MIR1225, RNA5SP410, and TMEM256-PLSCR3. Each is linked with SLC35A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC35A1-to-partner and partner-to-SLC35A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1225 grouped by SLC35A1-low versus SLC35A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A1→partner) and Y-score (partner→SLC35A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR1225 →	+0.274	+3.027	<.001	.007	3	3
UCEC	RNA5SP410 →	+0.787	+2.596	<.001	.001	3	2
UCEC	TMEM256-PLSCR3 →	+0.119	+3.701	<.001	.001	3	1
UCEC	CCNQ →	+0.393	+2.700	.003	.006	3	1
UCEC	MIR4701 →	+0.771	+2.463	.002	.002	3	1
UCEC	MIR4482 →	+0.918	+2.567	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,028 associations by consensus.

MIR1225 by SLC35A1 expression — UCEC

Explore this box plot interactively →