SLC35A1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC35A1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC35A1-associated genes across cancer lineages are CCDC63 and OR5V1. Each is linked with SLC35A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35A1-to-partner and partner-to-SLC35A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC63 grouped by SLC35A1-low versus SLC35A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35A1→partner) and Y-score (partner→SLC35A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECCDC63 →+0.048+3.920<.001.00531
LARGE_INTESTINEOR5V1 →+0.008+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CCDC63 by SLC35A1 expression — LARGE_INTESTINE

Box plot of CCDC63 in SLC35A1-low vs SLC35A1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration