SLC34A2

Across TCGA pan-cancer cohorts, SLC34A2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC34A2 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC34A2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC34A2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where SLC34A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.874	0.597	.011	23	view →
CCRCC	OS	Median	II,III,IV	0.940	0.692	.005	15	view →
LSCC	DFS	Median	All	0.914	0.956	.040	2	view →
HNSC	OS	Tertile	IV	1.000	0.567	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC34A2–LUAD (OS)

Open the LUAD breakdown →