SLC34A2

Across TCGA patient cohorts, SLC34A2 mutation is significantly associated with the RNA expression of many other genes, with 4,707 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC34A2-associated genes across cancer lineages are RPPH1-3P, TEDC2, and H2AZ1. Each is linked with SLC34A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC34A2-to-partner and partner-to-SLC34A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPPH1-3P grouped by SLC34A2-low versus SLC34A2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A2→partner) and Y-score (partner→SLC34A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RPPH1-3P →	+0.106	+5.742	<.001	.001	3	3
UCEC	TEDC2 →	+0.564	+2.243	<.001	<.001	3	3
UCEC	H2AZ1 →	+0.690	+2.939	<.001	<.001	3	3
UCEC	SCNN1B →	-1.324	-2.247	<.001	.001	3	3
UCEC	CKS1B →	+0.552	+1.947	.006	<.001	3	3
UCEC	PPP2R2D →	+0.258	+1.968	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,707 associations by consensus.

RPPH1-3P by SLC34A2 expression — LUSC

Explore this box plot interactively →