SLC34A2

Across TCGA patient cohorts, SLC34A2 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC34A2-associated genes across cancer lineages are PCNA, eEF2, and AMPK_alpha. Each is linked with SLC34A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC34A2-to-partner and partner-to-SLC34A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SLC34A2-low versus SLC34A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A2→partner) and Y-score (partner→SLC34A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PCNA →	+0.181	+2.000	.010	.027	3	3
SKCM	eEF2 →	+0.300	+1.502	.012	.028	3	2
SKCM	AMPK_alpha →	+0.194	+2.906	<.001	.001	3	2
SKCM	Src →	-0.297	-2.584	<.001	.010	3	2
COAD	14-3-3_beta →	-0.202	-1.974	.014	.031	3	2
COAD	EGFR_pY1068 →	-0.428	-3.169	.001	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

PCNA by SLC34A2 expression — SKCM

Explore this box plot interactively →