SLC34A2

Across TCGA cell cohorts, SLC34A2 mutation is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC34A2-associated genes across cancer lineages are COX4I2, IFNG, and SLITRK2. Each is linked with SLC34A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC34A2-to-partner and partner-to-SLC34A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX4I2 grouped by SLC34A2-low versus SLC34A2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A2→partner) and Y-score (partner→SLC34A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	COX4I2 →	+0.090	+5.087	<.001	.004	3	2
URINARY_TRACT	IFNG →	+0.006	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUSC	SLITRK2 →	+0.081	+3.662	<.001	.005	3	1
LUNG_NSCLC_LUSC	VWC2 →	+0.017	+4.137	.001	.001	3	1
LUNG_NSCLC_LUSC	SHISA6 →	+0.454	+3.662	<.001	.005	3	1
LUNG_NSCLC_LUSC	AFM →	+1.103	+3.832	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

COX4I2 by SLC34A2 expression — URINARY_TRACT

Explore this box plot interactively →