SLC34A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC34A1 mutation is significantly associated with the RNA expression of many other genes, with 798 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC34A1-associated genes across cancer lineages are RN7SKP186, RNU6-15P, and MIR103A1. Each is linked with SLC34A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC34A1-to-partner and partner-to-SLC34A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP186 grouped by SLC34A1-low versus SLC34A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A1→partner) and Y-score (partner→SLC34A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SKP186 →+0.071+3.186<.001.00632
SKCMRNU6-15P →+0.283+2.767<.001.00232
BRCAMIR103A1 →+0.787+4.539<.001.00532
BRCAPRAMEF36P →+0.012+7.473<.001.00732
LUADRNA5SP447 →+0.172+4.584<.001<.00132
LUADRNA5SP172 →+0.203+2.847.006.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 798 associations by consensus.

RN7SKP186 by SLC34A1 expression — SKCM

Box plot of RN7SKP186 in SLC34A1-low vs SLC34A1-high samples in SKCM.

Explore this box plot interactively →

Exploration