SLC34A1

Across TCGA patient cohorts, SLC34A1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC34A1-associated genes across cancer lineages are JNK_pT183_Y185, MSH2, and PDK1_pS241. Each is linked with SLC34A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC34A1-to-partner and partner-to-SLC34A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by SLC34A1-low versus SLC34A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A1→partner) and Y-score (partner→SLC34A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.179	-2.459	.014	.019	3	1
UCEC	MSH2 →	-0.239	-2.990	.018	.036	2	2
UCEC	PDK1_pS241 →	+0.158	+1.598	.034	.044	3	1
UCEC	Shc_pY317 →	-0.135	-2.807	.042	.003	3	1
UCEC	STAT3_pY705 →	-0.321	-3.311	.005	.010	3	1
UCEC	TIGAR →	+0.151	+2.833	.023	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

JNK_pT183_Y185 by SLC34A1 expression — UCEC

Explore this box plot interactively →