SLC34A1

Across TCGA cell cohorts, SLC34A1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC34A1-associated genes across cancer lineages are NANOGNB, KRTAP29-1, and MAGEB4. Each is linked with SLC34A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC34A1-to-partner and partner-to-SLC34A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NANOGNB grouped by SLC34A1-low versus SLC34A1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC34A1→partner) and Y-score (partner→SLC34A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	NANOGNB →	+0.025	+4.369	.001	.008	3	1
SKIN	KRTAP29-1 →	+0.026	+4.217	<.001	.001	3	1
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	IL9R →	+0.576	+3.125	<.001	.008	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.005	+2.777	.003	.004	3	1
LARGE_INTESTINE	FBXW10 →	+0.183	+3.491	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

NANOGNB by SLC34A1 expression — SOFT_TISSUE

Explore this box plot interactively →